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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Local delivery of USC-derived exosomes harboring ANGPTL3 enhances spinal cord functional recovery after injury by promoting angiogenesis

Fig. 7

ANGPTL3 present in USC-Exo mediates neurological functional recovery after SCI. a, b Distribution of BMS scores and withdrawal threshold per group throughout the 56 days. c Cross-sectional image of HE staining in the PBS-, USC-Con shRNA-Exo-, and USC-shANGPTL3-Exo-treated mice. Scale bar = 100 μm. d Quantitative data of the lesion cavities shown in c. e, f Representative electrophysiological traces and the quantitative data of amplitudes, latent period in the PBS-, USC-Con shRNA-Exo-, and USC-shANGPTL3-Exo-treated mice. The data are presented as the means ± SD; n = 6 per group. *p < 0.05, **p < 0.01 compared among different treatment groups

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