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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Local delivery of USC-derived exosomes harboring ANGPTL3 enhances spinal cord functional recovery after injury by promoting angiogenesis

Fig. 8

Exosomal ANGPTL3 in USC-Exo promotes angiogenesis at the spinal cord injury site. a Gross 3D view of spinal cord microvasculature in the injured spinal cord treated with PBS, USC-Con shRNA-Exo, and USC shANGPTL3 post-SCI; scale bar, 200 μm. b Quantitative analysis of the vascular morphological parameters shown in a. c Representative images of ki67/CD31 double staining of injured spinal cord sections treated with PBS, USC-Con shRNA-Exo, and USC shANGPTL3 post-SCI; scale bar, 50 μm. d Quantification of the number of ki67/CD31 double-positive cells shown in c. The data are presented as the means ± SD. *p < 0.05, **p < 0.01 compared among different treatment groups

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