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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Human umbilical cord mesenchymal stem cell-derived extracellular vesicles ameliorate airway inflammation in a rat model of chronic obstructive pulmonary disease (COPD)

Fig. 8

Mean linear intercept of the cigarette smoke-exposed group. Identification of the findings in the figures shown a representative histological sections stained with H&E staining for each group. b Semi-quantitative analysis of the mean linear intercept of CS-induced emphysema in rat lung. CS increased the mean linear intercept, and 2 weeks of self-healing failed to alleviate the alveolar obstruction. Meanwhile, treatment with hUC-MSC-EVs significantly reduced the mean linear intercept. hUC-MSCs and hUC-MSC-CM did not observe a significant reduction. *p < 0.05

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