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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Dental pulp stem cells can improve muscle dysfunction in animal models of Duchenne muscular dystrophy

Fig. 4

Regulation of inflammation associated with the DMD phenotype. a Serum levels of IL-6 from dogs quantified using ELISA during the experimental period. b Cross-sectional magnetic resonance images (MRI) in the lower leg muscles of untreated (control DMD) and hDPSC-treated CXMDJ (hDPSC-DMD). T2-weighted imaging was comparable in the lower legs (R, right side; L, left side, left/right asymmetry) of CXMDJ (untreated 13303MA and hDPSC-treated 13201MA and 13304MA). c Quantitative changes of higher T2-signals (signal-to-noise ratio, SNR) in the hindlimb muscles on CXMDJ shown in MRI data (b). Relative SNR was calculated from the highest signals in each hindlimb of 2-month-old compared to 7-month-old dogs. Data are represented as mean ± SD and statistical differences compared to control DMD (*P < 0.05), t test

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