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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Effect of sex-specific differences on function of induced hepatocyte-like cells generated from male and female mouse embryonic fibroblasts

Fig. 6

Global gene expression of miHep by whole transcriptome analysis. The heat maps represent (A) hepatocyte transcription factor genes, (B) fibroblast marker genes, (C) cell adhesion molecules (CAM)-related genes, (D) drug metabolism related gene including phase I, II enzyme and 3 transporter genes, (E) global CYP enzymes, and (F) epithelial–mesenchymal transition (EMT) pathway-related genes, respectively. Male MEF, male miHep, female miHep, male liver and female liver normalized with female MEF. male miHep / female miHep meant male miHep normalized with female miHep. Male liver / female liver meant male liver normalized with female liver. (G) Venn diagram of up (a) or down (b) regulated Cyp genes between male miHeps and male liver normalized with female male miHeps and liver, respectively

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Stem Cell Research & Therapy

ISSN: 1757-6512