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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: MSI-1436 improves EMS adipose derived progenitor stem cells in the course of adipogenic differentiation through modulation of ER stress, apoptosis, and oxidative stress

Fig. 2

Evaluation of apoptosis. The Muse® Annexin V & Dead Cell assay (a, b) results showing increased apoptosis in EMS ND cells. Data was supported by the analysis of genes involved in the regulation of apoptotic pathway: Bax (c), Bcl-2 (d), p21 (e), and p53 (f). The Muse® MultiCaspases assay results (g, h) indicate increased apoptosis in EMS cells. Furthermore, using RT-qPCR, expression of Casp-3 (i) and Casp-9 (j) was investigated. Results expressed as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001

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