TY - JOUR AU - Zhao, Xiaohong AU - Bian, Ruyu AU - Wang, Fan AU - Wang, Ying AU - Li, Xue AU - Guo, Yicheng AU - Zhang, Xiaorong AU - Luo, Gaoxing AU - Zhan, Rixing PY - 2021 DA - 2021/01/07 TI - GDF-5 promotes epidermal stem cells proliferation via Foxg1-cyclin D1 signaling JO - Stem Cell Research & Therapy SP - 42 VL - 12 IS - 1 AB - Epidermal stem cells (EpSCs) can self-renew, which are responsible for the long-term maintenance of the skin, and it also plays a critical role in wound re-epithelization, but the mechanism underlying EpSCs proliferation is unclear. GDF-5, also known as BMP-14, is a member of the BMP family and can be used as a self-renewal supporter. Here, we studied the effects of GDF-5 on mouse EpSCs proliferation mechanism in wound healing. SN - 1757-6512 UR - https://doi.org/10.1186/s13287-020-02106-7 DO - 10.1186/s13287-020-02106-7 ID - Zhao2021 ER -