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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors

Fig. 8

Dotplot geometric mean linear depictions of pluripotency-associated genes a Oct-4, b Sox2, c Nanog, d Klf4, and e Rex1 expression levels in hiPSCs analyzed by RT-qPCR. hiPSCs cultured in static conditions (P0) were used as a control reference sample. hiPSCs were analyzed following expansion in vertical-wheel bioreactors (P1 = day 6 and P2 = day 12). Expression was quantified relative to the housekeeping gene GAPDH and was normalized to static culture hiPSC level (= 1). RQ relative quantification

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Stem Cell Research & Therapy

ISSN: 1757-6512