Fig. 4

Changes in echocardiographic parameters in the transplanted hearts after cold storage with a preservation solution supplemented by N-CdM and H-CdM. The representative echocardiographic pictures are taken from M-mode recordings. Cardiac function and left ventricular size, as measured by echocardiographic parameters: a left ventricular ejection fraction (LVEF; as a percentage), b left ventricular fractional shortening (LVFS; as a percentage), c left ventricular internal dimension at end-systole (LVIDs; in millimeters), d left ventricular internal dimension at end-diastole (LVIDd; in millimeters), e stroke volume (SV; in microliter), f heart rate (HR; in beat per minute), g cardiac output (CO; in milliliter per minute), and h representative echocardiographic images of the transplanted heart in three groups. N-CdM and H-CdM indicate normoxic- and hypoxic-conditioned medium, respectively. Data represent mean ± standard error of the mean. One-way ANOVA/Kruskal-Wallis was applied in statistical analysis. *p < 0.05 vs. vehicle, #p < 0.05 vs. N-CdM