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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Human foreskin-derived dermal stem/progenitor cell-conditioned medium combined with hyaluronic acid promotes extracellular matrix regeneration in diabetic wounds

Fig. 5

Effect of hFDSPC-CM on collagen regeneration, maturation, and remodelling in wounds of db/db mice. a Masson staining for representative wound beds on day 14; collagen deposition is stained blue, bar = 200 μm. b Regenerated collagen content was analysed using Picrosirius red staining under a polarised light microscope. Collagen type III is visualised in green colour and collagen type I is visualised in orange/red colour, bar = 400 μm. c The percentage of collagen volume to tissue volume was quantified according to the Masson staining results. d Ratio of collagen I:III in wound beds of each group. Data are shown as means ± SD; n = 4; **p < 0.01, ***p < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512