Fig. 7From: Inflammatory cytokines-stimulated human muscle stem cells ameliorate ulcerative colitis via the IDO-TSG6 axisA schematic model of the anti-inflammatory effects of hMuSCs on DSS-induced IBD. IDO induced by IFN-γ and TNF-α catalyzes tryptophan metabolism to produce KYN or KYNA in hMuSCs. KYN or KYNA promotes TSG-6 production through activating AHR signaling pathway, and consequently alleviates IBDBack to article page