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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia

Fig. 3

Osteoclastic bone resorption is increased during CRA. a, b Representative three-dimensional thickness maps from micro-computed tomography (micro-CT) scans of the trabecular bone from the distal femur metaphysis of control and LLC-bearing mice. Scale bar, 1000 μm. cf Ratio of bone surface area to bone volume, ratio of bone volume to total volume, trabecular number, and cortical wall thickness were calculated. g, h The mRNA expression levels of osteoblastic and osteoclastic genes in control and LLC-bearing mice (n = 6/group). i, j The numbers of osteoblasts and osteoclasts in the trabecular bone from control and LLC-bearing mice were calculated (n = 6/group). Data are presented as the means ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001; assessed by Student’s t test

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