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Table 1 Osteogenesis-related proteins with differential expressions in the TMT proteomics

From: Dynamic proteomic profiling of human periodontal ligament stem cells during osteogenic differentiation

Uniprot ID Protein name Gene name Clustera Reference
Q12802 A-kinase anchor protein 13 AKAP13 1 [18]
P07355 Annexin A2 ANXA2 1 [19]
P35556 Fibrillin-2 FBN2 1 [20]
Q04771 Activin receptor type-1 ACVR1 2 [21]
P02765 Alpha-2-HS-glycoprotein AHSG 2 [22]
O00622 CCN family member 1 CCN1 2 [23]
P02452 Collagen alpha-1(I) chain COL1A1 2 [24]
P08123 Collagen alpha-2(I) chain COL1A2 2 [24]
P02461 Collagen alpha-1(III) chain COL3A1 2 [25]
Q96CG8 Collagen triple helix repeat-containing protein 1 CTHRC1 2 [26]
O75369 Filamin-B FLNB 2 [27]
P19883 Follistatin FST 2 [28]
P17302 Gap junction alpha-1 protein GJA1 2 [29]
P35052 Glypican-1 GPC1 2 [30]
O60565 Gremlin-1 GREM1 2 [31]
P50281 Matrix metalloproteinase-14 MMP14 2 [32]
Q32P28 Prolyl 3-hydroxylase 1 P3H1 2 [33]
Q92791 Endoplasmic reticulum protein SC65 P3H4 2 [34]
P16234 Platelet-derived growth factor receptor alpha PDGFRA 2 [35]
P50454 Serpin H1 SERPINH1 2 [36]
P36897 TGF-beta receptor type-1 TGFBR1 2 [37]
P37275 Zinc finger E-box-binding homeobox 1 ZEB1 3 [38]
Q03135 Caveolin-1 CAV1 4 [39]
Q9UP38 Frizzled-1 FZD1 4 [40]
P17936 Insulin-like growth factor-binding protein 3 IGFBP3 4 [41]
A1X283 SH3 and PX domain-containing protein 2B SH3PXD2B 4 [42]
P05186 Alkaline phosphatase, tissue-nonspecific isozyme ALPL 5 Not list out
P12109 Collagen alpha-1(VI) chain COL6A1 5 [43]
P35555 Fibrillin-1 FBN1 5 [44]
Q13491 Neuronal membrane glycoprotein M6-b GPM6B 5 [45]
P52926 High mobility group protein HMGI-C HMGA2 5 [46]
  1. aClusters from k-means clustering of Fig. 3