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Table 1 Osteogenesis-related proteins with differential expressions in the TMT proteomics

From: Dynamic proteomic profiling of human periodontal ligament stem cells during osteogenic differentiation

Uniprot ID

Protein name

Gene name

Clustera

Reference

Q12802

A-kinase anchor protein 13

AKAP13

1

[18]

P07355

Annexin A2

ANXA2

1

[19]

P35556

Fibrillin-2

FBN2

1

[20]

Q04771

Activin receptor type-1

ACVR1

2

[21]

P02765

Alpha-2-HS-glycoprotein

AHSG

2

[22]

O00622

CCN family member 1

CCN1

2

[23]

P02452

Collagen alpha-1(I) chain

COL1A1

2

[24]

P08123

Collagen alpha-2(I) chain

COL1A2

2

[24]

P02461

Collagen alpha-1(III) chain

COL3A1

2

[25]

Q96CG8

Collagen triple helix repeat-containing protein 1

CTHRC1

2

[26]

O75369

Filamin-B

FLNB

2

[27]

P19883

Follistatin

FST

2

[28]

P17302

Gap junction alpha-1 protein

GJA1

2

[29]

P35052

Glypican-1

GPC1

2

[30]

O60565

Gremlin-1

GREM1

2

[31]

P50281

Matrix metalloproteinase-14

MMP14

2

[32]

Q32P28

Prolyl 3-hydroxylase 1

P3H1

2

[33]

Q92791

Endoplasmic reticulum protein SC65

P3H4

2

[34]

P16234

Platelet-derived growth factor receptor alpha

PDGFRA

2

[35]

P50454

Serpin H1

SERPINH1

2

[36]

P36897

TGF-beta receptor type-1

TGFBR1

2

[37]

P37275

Zinc finger E-box-binding homeobox 1

ZEB1

3

[38]

Q03135

Caveolin-1

CAV1

4

[39]

Q9UP38

Frizzled-1

FZD1

4

[40]

P17936

Insulin-like growth factor-binding protein 3

IGFBP3

4

[41]

A1X283

SH3 and PX domain-containing protein 2B

SH3PXD2B

4

[42]

P05186

Alkaline phosphatase, tissue-nonspecific isozyme

ALPL

5

Not list out

P12109

Collagen alpha-1(VI) chain

COL6A1

5

[43]

P35555

Fibrillin-1

FBN1

5

[44]

Q13491

Neuronal membrane glycoprotein M6-b

GPM6B

5

[45]

P52926

High mobility group protein HMGI-C

HMGA2

5

[46]

  1. aClusters from k-means clustering of Fig. 3