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Table 4 Characteristics of dermal injections of ASCs embedded in scaffolds

From: Differences of embedding adipose-derived stromal cells in natural and synthetic scaffolds for dermal and subcutaneous delivery

Author (year)

Scaffold material

Subtype (intervention)

Specimens

ASCs

Gauge

Placement

ASCs/ml

Number

Dong et al. (2014) [21]

Polymer + protein

aPEG and bSH-HA + ASCs

Sprague-Dawley Rats

Rats

NR

Dorsum

1,000,000

3

Dong et al. (2017) [22]

Polysaccharide & polymer

aPEG and gelatin + ASCs

FVB mice

Murine

NR

Dorsum

1,000,000

10

Machula et al. (2014) [30]

Protein

Electrospun tropoelastin + ASCs

SCID congenic mice

Human

NR

Dorsum

756,000

6

Kim et al. (2016) [31]

Polymer + ECM

ECM protein + methylcellulose

+ASCs

Sprague-Dawley rats

Human

23 G

Dorsum

100,000

3

Cheng et al. (2017) [32]

Polysaccharide + protein

Chitosan + cbFGF + ASCs

C57/B6 mice

Human

25 G

Dorsum

2,000,000

4

Chitosan/gelatin+ ASCs + cbFGF

  1. dASCs adipogenically differentiated ASCs, aPEG polyethylene glycol, bSH-HA thiolated hyaluronic acid, cbFGF basic fibroblast growth factor