TGF-β/SMAD signaling regulation of mesenchymal stem cells in adipocyte commitment

Table 1 The comparisons of white, brown, and beige adipose tissue

Types of adipose tissue	Specific gene	Anatomy	Lipid droplet	Specific markers	Function
White adipose tissue	UCP1 negative	Abdomen subcutis	A large unilocular lipid droplet	Tcf21	Lipid storage, secrete hormones and cytokines
Brown adipose tissue	UCP1 positive	Neck supraclavicular regions	Multilocular lipid droplets	Zic1	Thermogenesis secrete hormones and cytokines
Beige adipose tissue	UCP1 positive	WAT	Multilocular lipid droplets	Tbx1, Epsti1 Cd137, Tmem26	Thermogenesis

WAT, white adipose tissue; UCP1, uncoupling protein 1; Tcf21, transcription factor 21; Zic1, zinc finger protein of the cerebellum 1; Tbx1, T-box 1; Epsti1, epithelial stromal interaction 1; Cd137, tumor necrosis factor receptor superfamily, member 9; Tmem26, transmembrane protein 26

ISSN: 1757-6512