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Table 1 The comparisons of white, brown, and beige adipose tissue

From: TGF-β/SMAD signaling regulation of mesenchymal stem cells in adipocyte commitment

Types of adipose tissueSpecific geneAnatomyLipid dropletSpecific markersFunction
White adipose tissueUCP1 negativeAbdomen subcutisA large unilocular lipid dropletTcf21Lipid storage, secrete hormones and cytokines
Brown adipose tissueUCP1 positiveNeck supraclavicular regionsMultilocular lipid dropletsZic1Thermogenesis secrete hormones and cytokines
Beige adipose tissueUCP1 positiveWATMultilocular lipid dropletsTbx1, Epsti1 Cd137, Tmem26Thermogenesis
  1. WAT, white adipose tissue; UCP1, uncoupling protein 1; Tcf21, transcription factor 21; Zic1, zinc finger protein of the cerebellum 1; Tbx1, T-box 1; Epsti1, epithelial stromal interaction 1; Cd137, tumor necrosis factor receptor superfamily, member 9; Tmem26, transmembrane protein 26