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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: MicroRNA-126 protects against vascular injury by promoting homing and maintaining stemness of late outgrowth endothelial progenitor cells

Fig. 4

Overexpression of miR-126 activates P13K/Akt/eNOS and ERK/VEGF signaling pathways in LOCs. Western blotting shows immunochemistry signals of ERK, phosphorylated-ERK (p-ERK), VEGF, Akt, p-Akt, and eNOS in LOCs infected with lenti-vector or lenti-miR-126 (a). Quantification of p-ERK (b), VEGF (c), p-Akt (d), and eNOS (e) bands. GADPH expression was used for protein level normalization for VEGF and eNOS. Data are presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 vs. respective control group; n ≥ 3

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