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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: MicroRNA-126 protects against vascular injury by promoting homing and maintaining stemness of late outgrowth endothelial progenitor cells

Fig. 7

miR-126 modulates LOC stemness by targeting KLF-8. Relative gene expression was determined for Oct-4 (a), sox-2 (b), Nanog (c), and Rex-1 (d) by real-time PCR after transfection with sh-KLF-8 or sh-NC. Relative gene expression was determined for Oct-4 (e), sox-2 (f), Nanog (g), and Rex-1 (h) by real-time PCR after transfected with lenti-miR-126, lenti-miR-NC and co-transfected with lenti-miR-126 and lenti-KLF-8. KLF-8 protein (i, j) expression in LOCs transfected with lenti-miR-126 and lenti-miR-NC and co-transfected with lenti-miR-126 and lenti-KLF-8. Data are presented as mean ± SD. **P < 0.01 and ***P < 0.001, vs. respective control group; n ≥ 3

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