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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: MicroRNA-126 protects against vascular injury by promoting homing and maintaining stemness of late outgrowth endothelial progenitor cells

Fig. 8

Effect of transplantation of lenti-miR-126-infected LOCs on reendotheliazation after carotid balloon injury in GK rats. Representative CD31 stained (red) cross sections of the injured carotid artery at day 7 after balloon injury in GK rats injected with PBS, or LOCs transfected with lenti-vector, or lenti-miR-126, or negative control or miR-126 inhibitor (a, × 200). Merged parts represent modified LOCs which are indicted by white arrows (× 200). Evans blue staining of injured carotid arteries (b) and quantification of reendotheliazation area ratio from Evans blue staining (c). CD31 immunohistochemical staining of carotid arteries from the above different groups at 28th day after injury (d, × 100). Red arrows indicate CD31 positive. *P < 0.05, **P < 0.005, ***P < 0.001, mean ± SD, n = 4. Scale bar = 100 μm

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