Fig. 9

Effects of transplantation of lenti-miR-126 infected LOCs on neointimal hyperplasia in injured carotid arteries. HE staining of injured arteries 28 days after balloon injury in GK rats injected with PBS, or LOCs transfected with lenti-miR-126, or miR-126 inhibitor or their respective control or sham group (a, × 40), and red boxed areas are shown in panels below (a, × 400). Lines were used to indicate where the intima is and where the media is. Quantification of intima area (b) and intima/media ratios (c). *P < 0.05, **P < 0.01, ***P < 0.001 vs. PBS control; #P < 0.05 vs. lenti-vector infected LOCs; mean ± SD, n = 4. Scale bar = 100 μm