|Property of microfluidic systems||Benefit for cell culture|
|Small chip size and microchannels on the cellular length scale (5–500 μm)||-Reduced sample/reagent consumption|
-Numerous cell coculture in a single device
-Faster transfer of cell culture medium and heat, i.e., short equilibration time
|2D or 3D network and structure||-Simulating in vivo cell growth development|
|The feasibility to integrate multiple microfluidic devices on a chip||-Integrate with fluid handling operations for efficient and high-throughput cellular analysis|
-Integrate with detection functionality for in situ monitoring of cellular events
-Integrate with functionality for temperature control of the cellular microenvironment etc.