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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Systemic conditioned medium treatment from interleukin-1 primed mesenchymal stem cells promotes recovery after stroke

Fig. 2

Effect of αCM treatment at the time of stroke on lesion volume and functional recovery. Representative T2-weighted MRI scans (a) conducted at day 2 post-stroke and quantification (b). Changes in body mass over 14 days post-stroke expressed as percentage of baseline (c) and 28-point neurological score (d). Percentage of anti-clockwise rotations in the open field test at 24 h post-stroke (e) and latency to fall in accelerating rotarod (f). Burrowing behaviour (g) and nest building (h) tests were used as measures of well-being. Neuroscore and nest building data were expressed as median ± IQR. All other data were expressed as mean ± SD. Sham + vehicle, n = 10; sham + αCM, n = 10; stroke + vehicle, n = 9; stroke + αCM, n = 9. *p < 0.05

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