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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Umbilical cord-matrix stem cells induce the functional restoration of vascular endothelial cells and enhance skin wound healing in diabetic mice via the polarized macrophages

Fig. 2

UCMSCs or UCMSC-CM increases the percentage of M2 macrophages in the local wounds of diabetic mice. a Frozen sections of wound bed tissues from diabetic mice at 3 days after treatment were immunostained with specific antibodies against F4/80, CD206, and Ly6C. Nuclei were stained with DAPI (blue). Scale bar 100 μm. b Frequency of F4/80-positive macrophages in wound bed tissue. c Frequency of CD206- and F4/80-positive macrophages in wound bed tissue. d Frequency of Ly6C-positive cells in wound bed tissue. e The level of arginase-1 expression in wound bed tissues. n = 6 per group. *P < 0.05, **P < 0.01

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