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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Umbilical cord-matrix stem cells induce the functional restoration of vascular endothelial cells and enhance skin wound healing in diabetic mice via the polarized macrophages

Fig. 6

PGE2 mediates the polarization effects of UCMSC-CM on macrophages. LPS-treated macrophages were stimulated with NS-398-CM, a mixture of UCMSC-CM with an anti-PGE2 neutralizing antibody, or NCM plus PGE2. Several cytokines derived from macrophages were detected by ELISA. a TNF-α. b IL-6. c IL-10. d VEGF. n = 6 per group. *P < 0.05, **P < 0.01

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