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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion

Fig. 2

Radiographic analysis of fracture healing. a Representative radiological images of the control, CM-Exo and Exo groups at 8, 14 and 20 weeks after surgery. (Radiological examination 8 weeks after the surgery was performed to confirm successful nonunion modelling). b Representative micro-CT images of a nonunion femur at 20 weeks after surgery. c Radiographic score for X-ray images on postoperative weeks 8, 14 and 20, n = 5. d BV/TV on postoperative week 20 was quantified, n = 3. e Bone union rate was calculated by chi-square test in the control, CM-Exo and Exo groups. Abbreviations: 8w, 8 weeks; CM, conditioned medium; CM-Exo, exosome-depleted conditioned medium; Exo, exosomes; BV, bone volume; TV, total volume. **P < 0.01; ***P < 0.001

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