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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion

Fig. 6

BMMSC-Exos entered MC3T3-E1Cs and HUVECs and promoted the proliferation of the cells. a, b Laser scanning confocal microscopy analysis of the internalization of PKH26-labelled BMMSC-Exos by MC3T3-E1Cs (a) and HUVECs (b). The red-labelled exosomes were visible in the perinuclear region of recipient cells. c, d EdU incorporation by the control and Exo groups of MC3T3-E1Cs (c) and HUVCs (d) was visualized using a fluorescence microscope. The percentage of EdU-positive cells for each group was quantitated using ImageJ software (right graph), n = 3. Abbreviation: Exo, exosomes. *P < 0.05 vs the control group

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Stem Cell Research & Therapy

ISSN: 1757-6512