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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Mesenchymal stem cell-derived exosomes ameliorate cardiomyocyte apoptosis in hypoxic conditions through microRNA144 by targeting the PTEN/AKT pathway

Fig. 6

The transfected miR-144 mimics affect H9C2 cell apoptosis and p-AKT/AKT expression levels in the context of hypoxia. A Identification of transfected miR-144 mimics and mimics control. ###P < 0.001 vs. mimics control. B1B3 H9C2 cells transfected with miR-144 mimics had decreased cell apoptosis in hypoxic conditions. ###P < 0.001 vs. normoxia; **P < 0.01 vs. hypoxia+ mimics control. C1C3 H9C2 cells transfected with miR-144 mimics had altered p-AKT/AKT expression levels in hypoxic conditions. ###P < 0.001 vs. normoxia; ##P < 0.01 vs. normoxia; ***P < 0.001 vs. hypoxia+ mimics control. P-AKT/AKT, phosphorylated protein kinase B. Statistics calculated based on the results of three repetitions of each experiment

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