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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: miR-765 inhibits the osteogenic differentiation of human bone marrow mesenchymal stem cells by targeting BMP6 via regulating the BMP6/Smad1/5/9 signaling pathway

Fig. 6

miR-765 targets the 3′-UTR of BMP6. a The ability of miR-765 to impact BMP6 expression over the course of osteogenic differentiation in hMSCs following stable lentiviral transfected was assessed. b The miR-765 binding region in the BMP6 3′-UTR. c Luciferase activity assay. All values are expressed as means ± SD (X ± SD, n = 3). **P < 0.01 vs. negative controls, respectively. Note: NC: negative control; OE: miR-765 overexpression; sh: shRNA

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