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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Targeted silencing of miRNA-132-3p expression rescues disuse osteopenia by promoting mesenchymal stem cell osteogenic differentiation and osteogenesis in mice

Fig. 6

Targeted silencing of miRNA-132-3p improves osteogenic differentiation and osteogenesis in vivo. a The osteogenic differentiation phenotype was evaluated by determining the expression of Runx2, Osx, Alp, and Col1a1. b Fluorescent images of the calcein sediments in the region of bone formation. Scale bar = 50 μm. c Comparisons of mineral apposition rate (MAR) and bone formation rate per bone surface (BFR/BS) of the representative fluorescence images were calculated and analyzed. Values are shown as mean ± SD, n = 6. *P < 0.05. NS, no significant

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Stem Cell Research & Therapy

ISSN: 1757-6512