Fig. 7

Effect of FAK and ERK inhibition in a fiber-conditioned MSCs and b its protein secretory profiles. MSCs were treated with FAK (PF573228; 20 μM) and ERK (PD98059; 70 μM) inhibitors. a Real-time PCR data represent the mean ± SD, n = 6 per group, from 3 independent experiments. b Luminex assay data represent the mean ± SD, n = 4 per group, from 2 MSC donors. ŧ denotes p < 0.05 compared to the aligned fibers. # denotes p < 0.05 between MSC treated with PF573228 and their respective non-treated MSCs; † denotes p < 0.05 between MSC treated with PD98059 and their respective non-treated MSCs