Isolation methods | Separation basis | Purity | Recovery rate |
---|---|---|---|
Differential centrifugation with addition of 30% sucrose buffer solution | Density, size, etc. | High | |
Precipitation | Polymer precipitation | Low | |
Flushing separation | Positive charge adsorption | High | Low [30] |
Ultrafiltration | Size | High | |
Immunomagnetic bead method | Antigen-antibody specific reaction | High | |
Microfluidic separation | Density, size, etc. | High | |
Mass spectrometry | Ion-to-mass ratio | High |