Fig. 4

Immunologic surface markers. a MHC complex I and II expression. b Toll-like receptor (TLR) 4 expression. c Flow cytometry of BD-MSCs (passage 3) stained for MHC I, II, and TLR 4. The upper panel shows unstained cells. d, e Quantitative PCR (qPCR) expression of TLR 4 compared to human fibroblasts (Fb). e QPCR expression of TLR 1–10 expression compared to human peripheral blood mononuclear cells without statistical significance. Statistical significance is indicated with asterisks: *p value ≤0.05, ** p ≤ 0.01, and *** p ≤ 0.001. No asterisks represent p > 0.05. N = 3 for each group (=cells from 3 different patients per group); triplicates per biological sample. Graph: Mean with SEM