Fig. 4

MiR-672 regulates vascularization in vivo.a Micro-CT scanning of newly regenerated blood vessels in the defect regions repaired by CPC scaffold seeded with the ADSCs/Lenti-miR-672, ADSCs/Lenti-as-miR-672, and ADSCs/Lenti-miR-NC groups (within the white circle). b Histological observation of newly formed blood vessels in the regenerated bone tissue indicated by the perfused Microfil (black arrow). c Analyses of the blood vessel volume, percentage of blood vessel volume/total volume, and Microfil-labeled blood vessel number in the respective groups. Statistical significances were determined by unpaired Student’s t test using GraphPad Prism Version 8. *P < 0.05, **P < 0.01, ***P < 0.001