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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Alpha-enolase (ENO1), identified as an antigen to monoclonal antibody 12C7, promotes the self-renewal and malignant phenotype of lung cancer stem cells by AMPK/mTOR pathway

Fig. 6

Analysis of downstream pathway of ENO1 in lung cancer. a KEGG pathway analysis of putative targets were shown. AMPK signaling pathway, as a central regulator of cellular and organismal metabolism, was selected for further confirmation. b Western blotting verified the expression of proteins-related to AMPK/mTOR pathway in ENO1 knockdown or overexpression sphere cells. Data are expressed as mean ± SEM of three independent experiments. *p < 0.05, **p < 0.01, compared to control (CON)

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Stem Cell Research & Therapy

ISSN: 1757-6512