Fig. 6From: KAT6A regulates stemness of aging bone marrow-derived mesenchymal stem cells through Nrf2/ARE signaling pathwayGraphic summary shows the mechanism of decreased KAT6A-mediated stemness impairment in aging BMSCs. KAT6A was downregulated in aging BMSCs; this downregulation resulted in Nrf2/ARE signaling pathway inhibition and ROS accumulation, which further led to stemness impairmentBack to article page