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Table 1 Inclusion and exclusion criteria

From: Mesenchymal stem cells derived from perinatal tissues for treatment of critically ill COVID-19-induced ARDS patients: a case series

Inclusion criteria Exclusion criteria
• Available informed consent
• Male or female, 18–70 years of age
• Evidence of pneumonia by chest X-ray or CT scan and/or confirmation of SARS-CoV-2 by qRT-PCR
• ARDS diagnosed and SpO2/FiO2 ≤ 315
• SOFA score between 2 and 13
• Required mechanical ventilation and/or supplemental oxygen
• Presence of severe allergic reaction after stem cell infusion
• Psychosis or under treatment for malignancy
• Co-infection with HIV, tuberculosis, adenovirus, or other respiratory infections virus
• Patient with previous history of pulmonary embolism
• Anticipated death within 48 h
• Continuous use of immunosuppressive agents or organ transplant within the past 6 months
• Pregnancy or breastfeeding
  1. ARDS acute respiratory distress syndrome, SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, CT computed tomography, SOFA Sequential Organ Failure Assessment