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Table 1 Quantitative analysis of vascular function

From: Mesenchymal stem cell-derived conditioned medium protects vascular grafts of brain-dead rats against in vitro ischemia/reperfusion injury

 

KCl (g)

PE (% of KCl)

pD2 to PE

Rmax to ACh (%)

pD2 to ACh

Rmax to SNP (%)

pD2 to SNP

BD

4.4 ± 0.1

69 ± 4

6.8 ± 0.1

81 ± 2

7.1 ± 0.1

100 ± 0

9.4 ± 0.1

BD-IR

2.7 ± 0.2*

132 ± 10*

7.1 ± 0.1*

50 ± 3*

6.7 ± 0.1

100 ± 0

9.1 ± 0.1

BD-IR+CM

2.8 ± 0.1*

91 ± 6*,#

6.6 ± 0.1#

72 ± 2#

7.3 ± 0.1#

99 ± 0

9.3 ± 0.1

  1. KCl potassium chloride, PE phenylephrine, ACh acetylcholine, SNP sodium nitroprusside, IR ischemia/reperfusion, CM conditioned medium, BD brain death, Rmax maximum relaxation, pD2, -logEC50 EC50 being the concentration of substance that elicited 50% of the maximum response. Values are means ± SEM
  2. *p < 0.05 vs. BD, #p < 0.05 vs. BD-IR
  3. n = 26–34 rings from 7 to 9 rats