| KCl (g) | PE (% of KCl) | pD2 to PE | Rmax to ACh (%) | pD2 to ACh | Rmax to SNP (%) | pD2 to SNP |
---|
BD | 4.4 ± 0.1 | 69 ± 4 | 6.8 ± 0.1 | 81 ± 2 | 7.1 ± 0.1 | 100 ± 0 | 9.4 ± 0.1 |
BD-IR | 2.7 ± 0.2* | 132 ± 10* | 7.1 ± 0.1* | 50 ± 3* | 6.7 ± 0.1 | 100 ± 0 | 9.1 ± 0.1 |
BD-IR+CM | 2.8 ± 0.1* | 91 ± 6*,# | 6.6 ± 0.1# | 72 ± 2# | 7.3 ± 0.1# | 99 ± 0 | 9.3 ± 0.1 |
- KCl potassium chloride, PE phenylephrine, ACh acetylcholine, SNP sodium nitroprusside, IR ischemia/reperfusion, CM conditioned medium, BD brain death, Rmax maximum relaxation, pD2, -logEC50 EC50 being the concentration of substance that elicited 50% of the maximum response. Values are means ± SEM
- *p < 0.05 vs. BD, #p < 0.05 vs. BD-IR
- n = 26–34 rings from 7 to 9 rats