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Table 2 List of 23 factors involved in apoptosis, inflammation, and oxidative stress in conditioned medium

From: Mesenchymal stem cell-derived conditioned medium protects vascular grafts of brain-dead rats against in vitro ischemia/reperfusion injury

Properties

Factors

Anti-apoptotic

TIMP-1, growth hormone, growth hormone receptor, EG-VEGF (PK1), VEGF, VEGF-C, activin A, BDNF, FGF-BP

Pro-apoptotic

TRAIL, thrombospondin, TROY, Fas ligand/TNFSF6

Anti-inflammatory

CXCR-4, MDC

Pro-inflammatory

CINC-2, CINC-3, FSL-1, MCP-1, MDC, MIF, MIP-1α, MMP-13, TLR4, Fas ligand/TNFSF6, CXCR-4

Protection from oxidative stress

FGF-BP

  1. TIMP-1 tissue inhibitors of metalloproteinases-1, EG-VEGF endocrine gland-derived vascular endothelial growth factor, PK1 prokineticin-1, VEGF vascular endothelial growth factor, VEGF-C vascular endothelial growth factor-C, BDNF brain-derived neurotrophic factor, FGF-BP fibroblast growth factor-binding protein, TRAIL tumor necrosis factor-related apoptosis-inducing ligand, TROY tumor necrosis factor receptor superfamily, member-19, TNFSF6 tumor necrosis factor superfamily, member-6, CXCR-4 C-X-C chemokine receptor type-4, MDC macrophage-derived chemokine, CINC cytokine-induced neutrophil chemoattractant, FSL-1 follostatin-like-1, MCP-1 monocyte chemoattractant protein-1, MIF macrophage migration inhibitory factor, MIP-1α macrophage inflammatory proteins 1-alpha, MMP-13 matrix metalloproteinase-13, TLR4 Toll-like receptor-4
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Stem Cell Research & Therapy

ISSN: 1757-6512