Fig. 5
From: Intrapancreatic MSC transplantation facilitates pancreatic islet regeneration
The morphometry of pancreatic islets after ADMSC administration in STZ-induced diabetic mice. a Pancreatic histological analysis of proliferating islet cells tagged with BrdU (brown color) within the islets (insulin stain in blue color) was achieved with immunohistochemistry. b The number of BrdU-positive cells per section replicating within the islets. c Islet area was significantly increased in the IPR group compared to others and d islet per section also adopted an identical trend. e, f The insulin content measured with ELISA in the pancreas and blood of their respective groups. STZ, streptozotocin; IPR, intrapancreatic route; BrdU, bromodeoxyuridine; IVR, intravenous route; no STZ and no MSC, control. Data represent the mean ± SEM, n = 6, *p ≤ 0.05