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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: STAT3 activation by catalpol promotes osteogenesis-angiogenesis coupling, thus accelerating osteoporotic bone repair

Fig. 5

Angiogenic effects caused by catalpol treatment were partially abolished after STAT3-knockdown in BMSCs. VEGF expression and secretion of BMSCs was measured by a, b western blotting and c ELISA tests. d Diagram of groups dividing and treatment respectively, The pro-angiogenic ability of treated BMSCs was assessed via e, h scratch wound assay, f, i transwell migration assay, and (g, j) tube formation assay. The data are presented as means ± SEM. All experiments were repeated at least 3 times independently. **p < 0.01 vs. control group, ##p < 0.01 vs. STAT3-vehicle group

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