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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: RETRACTED ARTICLE: MiR-34a inhibitor protects mesenchymal stem cells from hyperglycaemic injury through the activation of the SIRT1/FoxO3a autophagy pathway

Fig. 1

Hyperglycaemia damaged the proliferation and paracrine ability of MSCs. MSCs were obtained from control or DM rats. Other MSCs were from normal rats and cultured with normal or high glucose medium for 28 days. a Cell viability was determined by CCK8 assay. b Cellular senescence was analysed by SA-β-gal staining. c Expression of VEGF and bFGF were measured by ELISA. d QRT-PCR analysis was applied to detect the expression of miR-34a. Each column represents mean ± SD from three independent experiments. *P < 0.05

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