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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: RETRACTED ARTICLE: MiR-34a inhibitor protects mesenchymal stem cells from hyperglycaemic injury through the activation of the SIRT1/FoxO3a autophagy pathway

Fig. 3

MiR-34a influences the expression of autophagy factors under hyperglycaemic conditions. MSCs were cultured with normal or high glucose medium for 28 days with or without transfection with miR-34a mimic, NC or miR-34a inhibitor for 48 h, respectively. a, b The protein level of SIRT1 and FoxO3a, and autophagy-related protein LC3 and Beclin1 were determined by western blot. c Autophagic corpuscle was detected by TEM. Data are presented as mean ± SD of three separate experiments. *P < 0.05 vs. NG group. #P < 0.05 vs. HG group

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Stem Cell Research & Therapy

ISSN: 1757-6512