Table 3 Functional enrichment table performed with EPC-related genes on a database of mouse phenotype. Columns respectively describe the database employed during the functional enrichment, mouse phenotype identifier with their description, and number of genes found to be implicated in the enriched phenotype with respective p values for each phenotype (p values of enrichment were obtained with Toppgene application)
Database | Mouse phenotype identifiers | Mouse phenotype description | Number of EPC-related genes implicated | p values of enrichment |
|---|---|---|---|---|
Mouse Phenotype | MP:0000260 | Abnormal angiogenesis | 8 | 2.254E−7 |
Mouse Phenotype | MP:0002191 | Abnormal artery morphology | 8 | 1.953E−6 |
Mouse Phenotype | MP:0000259 | Abnormal vascular development | 8 | 2.402E−6 |
Mouse Phenotype | MP:0001614 | Abnormal blood vessel morphology | 10 | 1.440E−5 |
Mouse Phenotype | MP:0005602 | Decreased angiogenesis | 4 | 2.439E−5 |
Mouse Phenotype | MP:0005592 | Abnormal vascular smooth muscle morphology | 4 | 3.091E−5 |
Mouse Phenotype | MP:0003227 | Abnormal vascular branching morphogenesis | 3 | 5.270E−5 |