Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Induced neural stem cell grafts exert neuroprotection through an interaction between Crry and Akt in a mouse model of closed head injury

Fig. 5

Crry expression and Akt activation in iNSC-derived neurons treated with CR2-Crry. a, b RT-QPCR was utilized to determine the expression of the Crry (a) and Akt (b) genes in neurons derived from iNSCs among the PBS (neurons receiving PBS treatment), CHI (neurons receiving CHI mouse serum treatment), and CHI+CR2-Crry (neurons receiving CHI mouse serum and CR2-Crry treatment) groups (n = 3/group; one-way ANOVA, *P < 0.05, **P < 0.01, ***P < 0.001). c Representative immunoblots depicting the levels of C3d, C9, Crry, active Caspase-3, p-AKT, and AKT in neurons derived from iNSCs among the three groups. dj Histograms showing the relative levels of C3d (d), C9 (e), Crry (f), active Caspase-3 (g), p-AKT (h), AKT (i), and p-AKT/AKT (j) in neurons derived from iNSCs among the three groups (n = 6/group; one-way ANOVA, *P < 0.05, **P < 0.01, ***P < 0.001)

Back to article page