Fig. 6

Enhanced homing of Ad-MSCs co-expressing CXCR4 and IL10 into the inflamed pads. a Representative flow cytometry analyses of CFSE-labeled Ad-MSCs in the lungs from mice pre-treated with LPS (local administration in one pad) and infused with WT or mRNA-transfected MSCs. b Quantification of the presence of Ad-MSCs-CFSE⁺ in the lungs. c Representative flow cytometry analyses of CFSE-labeled Ad-MSCs in the inflamed pads from mice pre-treated with LPS (local administration in one pad) and infused with WT or mRNA-transfected MSCs. d Quantification of the presence of Ad-MSCs-CFSE⁺ in the inflamed pads. Analyses were conducted 24 h after the infusion of Ad-MSCs. Bars represent the mean ± SEM of at least n = 10 mice/group using Dunn’s multiple comparison test. *p < 0.05; versus WT-MSCs