Therapeutic method/compound | MSC type | Functional regulation and mechanism | References |
---|---|---|---|
Mg | Rat bone marrow mesenchymal stem cells | Reduce the risk of apoptosis induced by ultraviolet radiation | Chen Y et al., J Biomed Mater Res A, 2019 [87] |
17β-estradiol | UCB-MSCs | Increase the nuclear translocation of Nrf2 to protect UCB-MSCs from high glucose-induced mitochondrial ROS production, and thereby protect the cells from autophagic cell death | Oh JY et al., Free Radic Biol Med, 2019 [88] |
Pioglitazone | NP-MSCs | Decrease the compression-induced overproduction of ROS, protect cell viability and cell proliferation of NP-MSCs, and alleviate the toxic effects caused by compression | Hu Y et al., Oxid Med Cell Longev, 2019 [75] |
NAC and l-ascorbic acid 2-phosphate | AD-MSCs | Promote the growth of human AD-MSCs and suppress the oxidative stress-induced cell death by enhancing mitochondrial integrity and function | Li CJ et al., Oxid Med Cell Longev, 2017 [89] |