Fig. 8From: Therapeutic effects of peripherally administrated neural crest stem cells on pain and spinal cord changes after sciatic nerve transectionProposed molecular mechanisms involved in therapeutic effects of 3D-printed scaffold-based NCSC therapy to the spinal cord after SNT. Our study suggested that the inhibition of ERK and NF-κB signaling pathways contributes to the decreased activation of glial and improvement of PWMT and TPWL. The increased expression of BDNF and GAP-43 may contribute to nerve recoveryBack to article page