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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Propofol impairs specification of retinal cell types in zebrafish by inhibiting Zisp-mediated Noggin-1 palmitoylation and trafficking

Fig. 5

Propofol increases cell death and decreases the number of S-phase cells in retinas. a The number of terminal deoxynucleotidyl transferase dUTP nick-end labeling-positive cells (green) in the retinas of propofol-treated embryos (5 μg/ml propofol) at 36, 48, and 72 h postfertilization (hpf) is increased compared with that in controls. DNA, blue. n = 4. Scale bar, 25 μm. b EdU exposure at 36, 48, and 72 hpf decreases the proportion and mislocalization of S-phase cells in the retinas of propofol-treated embryos (5 μg/ml propofol) compared with control retinas. Error bars indicate the SEM. *, p < 0.05 and **, p < 0.01. n = 4. Scale bar, 18 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512