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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Mesenchymal stem cells modified by FGF21 and GLP1 ameliorate lipid metabolism while reducing blood glucose in type 2 diabetic mice

Fig. 1

Morphology and multilineage differentiation capacity of MSCs. a Adipose-derived MSCs showed a homogeneous spindle-shaped morphology. Bar = 100 μm. b Flow cytometric analysis of the phenotypic characterization of MSCs. The phenotypes of CD73, CD90, CD105, CD34, and CD45 expression by MSCs were detected by flow cytometry. The green lines indicate the fluorescence intensity of cells stained with the corresponding antibodies, and the red lines represent isotype-matched negative control cells. c Osteogenesis was examined by alizarin red S staining for mineral nodule deposition. Adipogenesis was observed by the presence of lipid vesicles and confirmed by oil red O staining. The picture in the red box shows the enlarged observation of lipid droplets in the cell. Bars = 100 μm

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