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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: mTOR inhibitor INK128 promotes wound healing by regulating MDSCs

Fig. 3

Accumulation of MDSCs in DM and promotion of high glucose on MDSCs. ac The accumulation of MDSCs was showed by flow cytometry in bone marrow, PBMC and spleen of DM and CON at day 3 after injury. df The accumulation of MDSCs in bone marrow, PBMC, and spleen at day 7 after injury was showed by flow cytometry. g, h MDSCs of skin tissue around the wound at day 3 and day 7 after injury were investigated by immunofluorescence staining. i The percentage of MDSCs was analyzed by flow cytometry in bone marrow cells from CM treated with the graded concentration of glucose in vitro. MDSCs, myeloid-derived suppressor cells; BM, bone marrow; CON, control mice; DM, diabetic mice; PBMC, peripheral blood mononuclear cell

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