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Fig. 9 | Stem Cell Research & Therapy

Fig. 9

From: Differential SOD2 and GSTZ1 profiles contribute to contrasting dental pulp stem cell susceptibilities to oxidative damage and premature senescence

Fig. 9

SOD isoform protein levels and total SOD activities during extended DPSC culture with or without exogenous H2O2 (50–200 μM) treatment. a–c Representative Western blot images and corresponding densitometric analysis of SOD1, SOD2, and SOD3 protein levels by high proliferative (10–25PDs and 40–65PDs) and low proliferative (2–10PDs) DPSC sub-populations. For all Western blots, images from one representative experiment of three are shown. Densitometry data was normalized versus β-actin loading controls, with values subsequently normalized versus untreated high proliferative DPSCs at early PDs (10–25PDs). A.U. = Arbitrary units. d Total SOD activities for high proliferative (10–25PDs and 40–65PDs) and low proliferative (2–10PDs) DPSC sub-populations. N = 3, values in the graphs represent mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001

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